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Pancreatic Neuroendocrine Carcinoma

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Associated Genetic Biomarkers

Overview

NCI Definition: An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the pancreas. The mitotic count is more than 20 per 10 HPF. According to the size of the malignant cells, the prominence of the nucleoli, and the amount of cytoplasm, it is classified either as small or large cell neuroendocrine carcinoma. [1]

Clinical Trials

View Clinical Trials for Pancreatic Neuroendocrine Carcinoma

Disease Details

Synonyms
CARCINOMA, ISLET CELL, MALIGNANT, Malignant Pancreatic Endocrine Tumor, pancreatic endocrine cancer, High-Grade Pancreatic Neuroendocrine Carcinoma, Pancreatic Endocrine Carcinoma, Islet Cell Carcinoma, Poorly Differentiated Pancreatic Endocrine Carcinoma, Pancreatic NEC G3, Pancreas neuroendocrine carcinoma, Malignant Islet Cell Tumor, Islet Cell Cancer, High Grade Pancreatic Neuroendocrine Carcinoma, Pancreatic NEC
Parent(s)
Pancreatic Neuroendocrine Neoplasm
Children
Pancreatic Small Cell Neuroendocrine Carcinoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.