Diseases /

Pancreatic Neuroendocrine Tumor

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Associated Genetic Biomarkers

Overview

NCI Definition: A low or intermediate grade well differentiated tumor with neuroendocrine differentiation that arises from the pancreas. According to the presence or absence of clinical syndromes that result from hormone hypersecretion, pancreatic neuroendocrine tumors are classified either as functional or nonfunctional. [1]

Biomarker-Directed Therapies

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Clinical Trials

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Disease Details

Synonyms
Islet cell tumors - pancreas, PanNET, Pancreas neuroendocrine tumor (pNET), Islet cell tumors of the pancreas, Islet Cell Tumor, Well Differentiated Pancreatic Endocrine Neoplasm, Well Differentiated Pancreatic Endocrine Tumor, Pancreas islet cell tumor, Pancreatic NET
Parent(s)
Pancreatic Neuroendocrine Neoplasm
Children
Pancreatic VIP-Producing Neuroendocrine Tumor, Pancreatic Gastrin-Producing Neuroendocrine Tumor, Pancreatic Insulin-Producing Neuroendocrine Tumor, Non-functioning Pancreatic Endocrine Tumor, Functional Pancreatic Neuroendocrine Tumor, and Pancreatic Delta Cell Neuroendocrine Tumor

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.