Overview

NCI Definition: A low or intermediate grade well differentiated tumor with neuroendocrine differentiation that arises from the pancreas. According to the presence or absence of clinical syndromes that result from hormone hypersecretion, pancreatic neuroendocrine tumors are classified either as functional or nonfunctional. [1]

Disease Details

Synonyms
Pancreatic NET, Islet cell tumors of the pancreas, Well Differentiated Pancreatic Endocrine Tumor, Well Differentiated Pancreatic Endocrine Neoplasm, PanNET, Islet Cell Tumor, Islet cell tumors - pancreas, Pancreas islet cell tumor, Pancreas neuroendocrine tumor (pNET)
Parent(s)
Pancreatic Neuroendocrine Neoplasm
Children
Non-functioning Pancreatic Endocrine Tumor, Functional Pancreatic Neuroendocrine Tumor, Pancreatic Insulin-Producing Neuroendocrine Tumor, Pancreatic Delta Cell Neuroendocrine Tumor, Pancreatic VIP-Producing Neuroendocrine Tumor, and Pancreatic Gastrin-Producing Neuroendocrine Tumor

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.