NCI Definition: A malignant tumor arising from the parenchymal cells of the parathyroid gland. It is associated with the symptoms of primary hyperparathyroidism, resulting from the excessive production of parathyroid hormone. Morphologically, the differential diagnosis from parathyroid gland adenoma may be difficult. A definitive diagnosis of carcinoma is made only in the presence of capsular invasion, vascular invasion, and/or perineural invasion. [1]

Disease Details

Parathyroid Gland Adenocarcinoma, Carcinoma of Parathyroid Gland, Parathyroid Carcinoma, Parathyroid cancer, NOS, Carcinoma of the Parathyroid Gland, parathyroid cancer, Adenocarcinoma of the Parathyroid Gland, Cancer of the Parathyroid Gland, Adenocarcinoma of the Parathyroid, Adenocarcinoma of Parathyroid, Parathyroid Adenocarcinoma, Carcinoma of Parathyroid, Carcinoma of the Parathyroid, Cancer of Parathyroid Gland, Adenocarcinoma of Parathyroid Gland, Parathyroid Cancer, Parathyroid Gland Cancer
Parathyroid Gland Neoplasm
OncoTree Name
Parathyroid Carcinoma
OncoTree Code


1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.