Overview

Pharyngeal squamous cell carcinomas most frequently harbor alterations in TP53, PIK3CA, KMT2D, CDKN2A, and FBXW7 [2].

Most Commonly Altered Genes in Pharyngeal Squamous Cell Carcinoma

TP53 Mutation, TP53 c.217-c.1178 Missense, TP53 Missense, PIK3CA Mutation, and KMT2D Mutation are the most common alterations in pharyngeal squamous cell carcinoma [2].

Top Alterations in Pharyngeal Squamous Cell Carcinoma

Disease Details

Parent(s)
Malignant Pharyngeal Neoplasm
Children
Hypopharyngeal Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma, and Nasopharyngeal Squamous Cell Carcinoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.