Overview

NCI Definition: Neoplasms that are located in the pineal gland. These neoplasms arise either from pineal parenchymal cells (pineocytes), as do pineocytomas and the more aggressive pineoblastomas, or from other cell types, as do pineal astrocytic tumors (notably pilocytic astrocytomas) and germ cell tumors. Clinical symptoms include neuro-ophthalmologic dysfunction, changes in mental status, dysfunction of the brain stem, and hypothalamic-based endocrine abnormalities. [1]

Significant Genes in Pineal Region Neoplasm

H3F3A +

Disease Details

Synonyms
Tumor of the Pineal Area, Pineal Region Tumor, Pineal Tumor, Tumor of Pineal Region, Neoplasm of Pineal Area, Neoplasm of Pineal Region, Pineal Body Tumor, Neoplasm of the Pineal Area, Pineal Neoplasm, Neoplasm of the Pineal Region, Pinealoma, Tumor of the Pineal Region, Pineal Body Neoplasm, Tumor of Pineal Area, Pineal Area Neoplasm, Pineal Area Tumor
Parent(s)
Supratentorial Neoplasm
Children
Benign Pineal Region Neoplasm, Papillary Tumor of the Pineal Region, Pineal Parenchymal Cell Neoplasm, Pineal Region Germ Cell Tumor, Pineal Region Meningioma, and Malignant Pineal Region Neoplasm
OncoTree Name
Pineal Tumor
OncoTree Code
PINT

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.