Overview

NCI Definition: A non-metastasizing tumor that arises from the adenohypophysial cells of the anterior lobe of the pituitary gland. The tumor can be hormonally functioning or not. The diagnosis can be based on imaging studies and/or radioimmunoassays. Due to its location in the sella turcica, expansion of the tumor mass can impinge on the optic chiasm or involve the temporal lobe, third ventricle and posterior fossa A frequently associated physical finding is bitemporal hemianopsia which may progress to further visual loss. [1]

Disease Details

Synonyms
Adenoma of the Pituitary Gland, Pituitary Adenoma, Adenoma of Pituitary, Adenoma of Pituitary Gland, Adenoma of the Pituitary, ADENOMA, ANTERIOR LOBE PITUITARY GLAND, BENIGN
Parent(s)
Anterior Pituitary Gland Endocrine Neoplasm
Children
Atypical Pituitary Gland Adenoma, ACTH-Producing Pituitary Gland Adenoma, Functioning Pituitary Gland Adenoma, TSH-Producing Pituitary Gland Adenoma, Prolactin-Producing Pituitary Gland Adenoma, Growth Hormone-Producing Pituitary Gland Adenoma, and Non-Functioning Pituitary Gland Adenoma
OncoTree Name
Pituitary Adenoma
OncoTree Code
PTAD

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.