Overview

NCI Definition: A rare adenocarcinoma with poor prognosis, arising from the adenohypophysial cells of the anterior lobe of the pituitary gland or pre-existing adenomas. The majority are hormonally functioning neoplasms, usually producing prolactin or ACTH. The diagnosis is based on the presence of metastases. Syndromes associated with pituitary gland carcinomas include hyperprolactinemia, Cushing disease, and acromegaly. [1]

Significant Genes in Pituitary Gland Carcinoma

EGFR +

Disease Details

Synonyms
Pituitary gland cancer, NOS, Carcinoma of the Pituitary Gland, Cancer of the Pituitary, Carcinoma of the Pituitary, Pituitary Carcinoma, Cancer of the Pituitary Gland, Cancer of Pituitary, Pituitary Gland Adenocarcinoma, Carcinoma of Pituitary Gland, Cancer of Pituitary Gland, Pituitary Gland Cancer, Carcinoma of Pituitary
Parent(s)
Malignant Pituitary Gland Neoplasm
Children
Growth Hormone-Producing Pituitary Gland Carcinoma, Basophilic Adenocarcinoma, ACTH-Producing Pituitary Gland Carcinoma, and TSH-Producing Pituitary Gland Carcinoma
OncoTree Name
Pituitary Carcinoma
OncoTree Code
PTCA

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.