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Poorly Differentiated Carcinoma, NOS

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Associated Genetic Biomarkers

Overview

Poorly differentiated carcinoma, NOSs most frequently harbor alterations in TP53, CDKN2A, KRAS, KMT2D, and ARID1A [2].

Most Commonly Altered Genes in Poorly Differentiated Carcinoma, NOS

TP53 Mutation, TP53 Missense, TP53 c.217-c.1178 Missense, KRAS Mutation, and KRAS Exon 2 Mutation are the most common alterations in poorly differentiated carcinoma, NOS [2].

Top Alterations in Poorly Differentiated Carcinoma, NOS

Clinical Trials

View Clinical Trials for Poorly Differentiated Carcinoma, NOS

Disease Details

Synonyms
Metastatic poorly differentiated carcinoma
Parent(s)
Carcinoma
OncoTree Name
Poorly Differentiated Carcinoma, NOS
OncoTree Code
PDC

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.