Associated Genetic Biomarkers


Poorly differentiated carcinoma, NOSs most frequently harbor alterations in TP53, CDKN2A, KRAS, KMT2D, and ARID1A [2].

Most Commonly Altered Genes in Poorly Differentiated Carcinoma, NOS

TP53 Mutation, TP53 Missense, TP53 c.217-c.1178 Missense, KRAS Mutation, and KRAS Exon 2 Mutation are the most common alterations in poorly differentiated carcinoma, NOS [2].

Top Alterations in Poorly Differentiated Carcinoma, NOS

Disease Details

Metastatic poorly differentiated carcinoma
OncoTree Name
Poorly Differentiated Carcinoma, NOS
OncoTree Code


1. National Cancer Institute. NCI Thesaurus Version 18.11d. [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.