Overview

NCI Definition: A plasma cell neoplasm that secretes an abnormal immunoglobulin, which deposits in tissues and forms a beta-pleated sheet structure that binds Congo red dye with characteristic birefringence. (WHO, 2001) [1]

Disease Details

Synonyms
Immunoglobulin Light Chain Amyloidosis, AL Amyloidosis
Parent(s)
Monoclonal Immunoglobulin Deposition Disease
Children
Primary Systemic Amyloidosis
OncoTree Name
Amyloidosis
OncoTree Code
MIDDA

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.