Overview

Primary central nervous system lymphomas most frequently harbor alterations in MYD88 and CDKN2A [2].

Most Commonly Altered Genes in Primary Central Nervous System Lymphoma

MYD88 Mutation are the most common alterations in primary central nervous system lymphoma [2].

Top Alterations in Primary Central Nervous System Lymphoma

Significant Genes in Primary Central Nervous System Lymphoma

AFF1 +

ALK +

BCL2 +

BCL6 +

ELL +

IDH1 +

IDH2 +

IRF4 +

KMT2A +

MLLT1 +

MLLT10 +

MLLT3 +

MLLT4 +

MYC +

Disease Details

Synonyms
PCNSL
Parent(s)
Central Nervous System Lymphoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.