Associated Genetic Biomarkers

Overview

NCI Definition: An anaplastic large cell lymphoma limited to the skin at the time of diagnosis. Most patients present with solitary or localized skin lesions, which may be tumors, nodules or papules. The t(2;5) translocation that is present in many cases of systemic anaplastic large cell lymphoma, is not found in this disease. (WHO, 2001) [1]

Disease Details

Synonyms
C-ALCL, Primary Anaplastic Large Cell Lymphoma of Skin, Primary Cutaneous CD30 Positive Anaplastic Large Cell Lymphoma, Primary Anaplastic Large Cell Lymphoma of the Skin, Primary Cutaneous CD30+ ALCL, Primary Cutaneous CD30+ Anaplastic Large Cell Lymphoma, ALCL, cutaneous, Anaplastic large-cell lymphoma, primary cutaneous type
Parent(s)
Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
OncoTree Name
Primary Cutaneous Anaplastic Large Cell Lymphoma
OncoTree Code
PCALCL

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.