Associated Genetic Biomarkers

Overview

NCI Definition: This entity represents a spectrum of lymphoproliferative disorders characterized by CD30 (Ki-1)-positive cutaneous T-cell infiltrates. The two ends of the spectrum include lymphomatoid papulosis (benign end) and primary cutaneous anaplastic large cell lymphoma (malignant end). Borderline lesions are also included in this spectrum. (WHO, 2001) [1]

Disease Details

Synonyms
Primary Cutaneous CD30+ T-Cell Lymphoproliferative Disorder, Primary Cutaneous CD30 Positive T-Cell Lymphoproliferative Disorders
Parent(s)
Mature T-Cell and NK-Cell Neoplasm
Children
Primary Cutaneous Anaplastic Large Cell Lymphoma
OncoTree Name
Primary Cutaneous CD30 Positive T-Cell Lymphoproliferative Disorders
OncoTree Code
PCLPD

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.