Overview

NCI Definition: A serous adenocarcinoma that arises from the lining of the peritoneum. It is characterized by high grade histopathologic features. [1]

Significant Genes in Primary Peritoneal High Grade Serous Adenocarcinoma

ATM +

BARD1 +

BRCA1 +

BRCA2 +

BRIP1 +

CDK12 +

CHEK1 +

CHEK2 +

FANCL +

PALB2 +

PIK3CA +

PPP2R2A +

RAD51B +

RAD51C +

RAD51D +

RAD54L +

Disease Details

Synonyms
Primary Peritoneal High-Grade Serous Adenocarcinoma
Parent(s)
Primary Peritoneal Serous Adenocarcinoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.