Diseases /
Prostate Neoplasm
Overview
NCI Definition: A benign, borderline, or malignant neoplasm that affects the prostate gland. Representative examples include benign prostate phyllodes tumor, prostatic intraepithelial neoplasia, prostate carcinoma, and prostate sarcoma. [1]
Prostate neoplasms most frequently harbor alterations in TP53, TMPRSS2, ERG, PTEN, and AR [2].
TP53 Mutation, TMPRSS2-ERG Fusion, TP53 Missense, TP53 c.217-c.1178 Missense, and AR Amplification are the most common alterations in prostate neoplasm [2].
Clinical Trials
Disease Details
References
1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.