Rectal Squamous Cell Carcinoma
Associated Genetic Biomarkers
NCI Definition: A very rare rectal carcinoma characterized by the presence of a malignant squamous cell infiltrate. 
There are 3 clinical trials for rectal squamous cell carcinoma, of which 3 are open and 0 are completed or closed. Of the trials that contain rectal squamous cell carcinoma as an inclusion criterion, 1 is phase 1/phase 2 (1 open) and 2 are phase 2 (2 open).
CDKN2A and HPV are the most frequent gene inclusion criteria for rectal squamous cell carcinoma clinical trials .
Bintrafusp alfa, prgn-2009, and nilotinib are the most common interventions in rectal squamous cell carcinoma clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.