Refractory Cytopenia with Unilineage Dysplasia
Associated Genetic Biomarkers
NCI Definition: A myelodysplastic syndrome characterized by dysplastic changes involving only one myeloid cell lineage in the bone marrow. It primarily affects older adults and includes refractory anemia, refractory neutropenia, and refractory thrombocytopenia. 
There is 1 clinical trial for refractory cytopenia with unilineage dysplasia, of which 1 is open and 0 are completed or closed. Of the trial that contains refractory cytopenia with unilineage dysplasia as an inclusion criterion, 1 is phase 2 (1 open).
Allogeneic hematopoietic stem cell transplantation and standard of care are the most common interventions in refractory cytopenia with unilineage dysplasia clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.