Associated Genetic Biomarkers

Overview

NCI Definition: A rare, low grade invasive adenocarcinoma of the breast characterized by the presence of cells that secrete milk-like material. Morphologically, it usually appears as a circumscribed lesion, composed of cystic spaces, tubular structures, and solid areas. [1]

Significant Genes in Secretory Breast Carcinoma

ETV6 +

NTRK1 +

NTRK2 +

NTRK3 +

Disease Details

Synonyms
Secretory Carcinoma of the Breast, Juvenile Secretory Carcinoma of Breast, Infiltrating Cystic Hypersecretory Duct Breast Carcinoma, Juvenile Carcinoma of the Breast, Cystic Hypersecretory Breast Carcinoma, Cystic Hypersecretory Carcinoma of Breast, Cystic Hypersecretory Carcinoma of the Breast, Invasive Cystic Hypersecretory Duct Breast Carcinoma, Juvenile Secretory Carcinoma of the Breast, Secretory Carcinoma, Juvenile Carcinoma of Breast, Juvenile Secretory Breast Carcinoma, Secretory Carcinoma of Breast, Juvenile Breast Carcinoma
Parent(s)
Breast Invasive Ductal Carcinoma
OncoTree Name
Juvenile Secretory Carcinoma of the Breast
OncoTree Code
JSCB

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.