Solitary Fibrous Tumor
NCI Definition: A localized neoplasm of probable fibroblastic derivation. It is characterized by the presence of round to spindle-shaped cells, hylanized stroma formation, thin-walled branching blood vessels, and thin bands of collagen. 
Solitary fibrous tumors most frequently harbor alterations in NAB2, STAT6, TP53, BCOR, and SETD2 .
NAB2-STAT6 Fusion, STAT6-NAB2 Fusion, TP53 Mutation, TP53 c.217-c.1178 Missense, and TP53 Missense are the most common alterations in solitary fibrous tumor .
There is 1 clinical trial for solitary fibrous tumor, of which 1 is open and 0 are completed or closed. Of the trial that contains solitary fibrous tumor as an inclusion criterion, 1 is phase 1/phase 2 (1 open).
Nivolumab and sunitinib are the most common interventions in solitary fibrous tumor clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.