Supraglottic Squamous Cell Carcinoma
Associated Genetic Biomarkers
NCI Definition: A squamous cell carcinoma of the larynx that arises from the supraglottic area. Signs and symptoms include dysphagia, a sensation of foreign body in the throat, and hemoptysis. It spreads to the space anterior to the epiglottis, pyriform sinus, and base of the tongue. 
There is 1 clinical trial for supraglottic squamous cell carcinoma, of which 1 is open and 0 are completed or closed. Of the trial that contains supraglottic squamous cell carcinoma as an inclusion criterion, 1 is no phase specified (1 open).
CDKN2A and HPV are the most frequent gene inclusion criteria for supraglottic squamous cell carcinoma clinical trials .
Chemotherapy and intensity-modulated radiation therapy are the most common interventions in supraglottic squamous cell carcinoma clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.