NCI Definition: A benign or malignant neoplasm that occurs within the intracranial cavity above the tentorium cerebelli. [1]

Supratentorial neoplasms most frequently harbor alterations in GNAS, PRKDC, FGFR1, FANCA, and CREBBP [2].

Most Commonly Altered Genes in Supratentorial Neoplasm

GNAS Mutation, PRKDC Mutation, FANCA Mutation, CREBBP Mutation, and ATM Mutation are the most common alterations in supratentorial neoplasm [2].

Top Alterations in Supratentorial Neoplasm

Disease Details

Supratentorial Tumors, Supratentorial Neoplasms, Brain Neoplasms, Supratentorial, Supratentorial Tumor
Brain Neoplasm
Diencephalic Neoplasm, Cerebral Neoplasm, Pituitary Gland Neoplasm, Rosette-Forming Glioneuronal Tumor of the Fourth Ventricle, and Pineal Region Neoplasm


1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.