NCI Definition: A benign or malignant neoplasm that occurs within the intracranial cavity above the tentorium cerebelli. [1]

Supratentorial neoplasms most frequently harbor alterations in PRKDC, ARID1B, ATM, ARID1A, and KMT2D [2].

Most Commonly Altered Genes in Supratentorial Neoplasm

PRKDC Mutation, ARID1B Mutation, ATM Mutation, ARID1A Mutation, and KMT2D Mutation are the most common alterations in supratentorial neoplasm [2].

Top Alterations in Supratentorial Neoplasm

Disease Details

Supratentorial Neoplasms, Brain Neoplasms, Supratentorial, Supratentorial Tumors, Supratentorial Tumor
Brain Neoplasm
Cerebral Neoplasm, Rosette-Forming Glioneuronal Tumor of the Fourth Ventricle, Pituitary Gland Neoplasm, Diencephalic Neoplasm, and Pineal Region Neoplasm


1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.