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T-Cell Large Granular Lymphocyte Leukemia

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Associated Genetic Biomarkers

Overview

NCI Definition: A T-cell peripheral neoplasm characterized by a persistent (>6 months) increase in the number of peripheral blood large granular lymphocytes, without a clearly identified cause. (WHO, 2001) [1]

Clinical Trials

View Clinical Trials for T-Cell Large Granular Lymphocyte Leukemia

Disease Details

Synonyms
T-Gamma Lymphoproliferative Disorder, Large Cell Granular Lymphogenous Leukemia, Tgamma Large Granular Lymphocyte Leukemia, T-cell large gran. lymph. leuk., LEUKEMIA, LARGE GRANULAR LYMPHOCYTIC, MALIGNANT, T-Cell Large Granular Lymphocytic Leukemia, Large Granular Lymphocytosis, Bone marrow leukemia T cell large granular (T-LGL), Large Cell Granular Lymphoid Leukemia, LGLL, T Gamma Lymphoproliferative Disorder, T-LGL leukemia, Large Granular Lymphocytic Leukemia
Parent(s)
Mature T-Cell and NK-Cell Neoplasm
OncoTree Name
T-Cell Large Granular Lymphocytic Leukemia
OncoTree Code
TLGL

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.