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Teratoma

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Overview

NCI Definition: A non-seminomatous germ cell tumor characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). It occurs in the testis, ovary, and extragonadal sites including central nervous system, mediastinum, lung, and stomach. According to the level of differentiation of the tissues which comprise the tumor, teratomas are classified as mature or immature. Mature teratomas are composed of well differentiated, adult-type tissues. Immature teratomas are composed of immature, fetal-type tissues. Testicular teratomas in children follow a benign clinical course. Mature ovarian teratomas without a fetal-type component have an excellent outcome. The prognosis of immature ovarian teratomas is related to the grade and stage of the tumor. [1]

Clinical Trials

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Disease Details

Synonyms
TERATOMA, UNDETERMINED
Parent(s)
Nongerminomatous Germ Cell Tumor
Children
Testicular Teratoma, Teratoma with Malignant Transformation, Malignant Teratoma, Central Nervous System Teratoma, Fallopian Tube Teratoma, Immature Teratoma, Gastric Teratoma, Childhood Teratoma, Cystic Teratoma, Mature Teratoma, Adult Teratoma, Mediastinal Teratoma, and Ovarian Teratoma
OncoTree Name
Teratoma
OncoTree Code
TT

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.