Testicular Germ Cell Tumor
NCI Definition: A germ cell tumor arising from the testis. Representative examples include teratoma, seminoma, embryonal carcinoma, and yolk sac tumor. 
Testicular germ cell tumors most frequently harbor alterations in KRAS, CDKN1B, CCND2, ETV6, and RAD52 .
CDKN1B Amplification, CCND2 Amplification, ETV6 Amplification, RAD52 Amplification, and KRAS Amplification are the most common alterations in testicular germ cell tumor .
There is 1 clinical trial for testicular germ cell tumor, of which 1 is open and 0 are completed or closed. Of the trial that contains testicular germ cell tumor as an inclusion criterion, 1 is phase 2 (1 open).
Nilotinib and paclitaxel are the most common interventions in testicular germ cell tumor clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.