Overview

NCI Definition: A lymphoma that arises from the testis and is not associated with lymphoma in another anatomic site. [1]

Testicular lymphomas most frequently harbor alterations in BCL2, XBP1, SUZ12, SOCS1, and ROS1 [2].

Most Commonly Altered Genes in Testicular Lymphoma

XBP1 E71K, SUZ12fs, SOCS1 S106R, ROS1 Mutation, and ROS1 L1475I are the most common alterations in testicular lymphoma [2].

Top Alterations in Testicular Lymphoma

Disease Details

Synonyms
Lymphoma of the Testis, Lymphoma of Testis, Primary Testicular Lymphoma
Parent(s)
Non-Hodgkin Lymphoma
Children
Testicular Diffuse Large B-Cell Lymphoma
OncoTree Name
Testicular Lymphoma
OncoTree Code
TLYM

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.