NCI Definition: A lymphoma that arises from the testis and is not associated with lymphoma in another anatomic site. 
Testicular lymphomas most frequently harbor alterations in BCL2, XBP1, SUZ12, SOCS1, and ROS1 .
XBP1 E71K, SUZ12fs, SOCS1 S106R, ROS1 Mutation, and ROS1 L1475I are the most common alterations in testicular lymphoma .
There are 2 clinical trials for testicular lymphoma, of which 2 are open and 0 are completed or closed. Of the trials that contain testicular lymphoma as an inclusion criterion, 2 are phase 2 (2 open).
Nivolumab and pembrolizumab are the most common interventions in testicular lymphoma clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.