Overview

NCI Definition: A malignant germ cell tumor arising from the testis. It is believed that it is derived from the sexually undifferentiated embryonic gonad. Treatment with radiotherapy is highly successful when the tumor is diagnosed in localized stages, which represents the majority of presentations of seminoma. [1]

Disease Details

Synonyms
Seminoma of the Testis, Seminoma of Testis, Testicular Seminoma Pure
Parent(s)
Testicular Pure Germ Cell Tumor
Children
Testicular Seminoma, Cribriform Variant, Testicular Spermatocytic Seminoma, Testicular Seminoma, Pseudoglandular Variant, and Testicular Seminoma, Tubular Variant

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.