Overview

NCI Definition: A neoplasm that affects the thymus. Representative examples include thymoma and carcinoma. [1]

Thymus neoplasms most frequently harbor alterations in TP53, CDKN2A, SOCS1, SETD2, and CDKN2B [2].

Most Commonly Altered Genes in Thymus Neoplasm

TP53 Mutation, TP53 c.217-c.1178 Missense, TP53 Missense, SOCS1fs, and SETD2 Mutation are the most common alterations in thymus neoplasm [2].

Top Alterations in Thymus Neoplasm

Disease Details

Synonyms
Neoplasm of the Thymus, Tumor of the Thymus, Thymic Neoplasm, Tumor of Thymus, Neoplasm of Thymus, Thymus Tumor, Thymic Tumor
Parent(s)
Thymus Disorder
Children
Malignant Thymus Neoplasm and Thymic Epithelial Neoplasm
OncoTree Name
Thymus
OncoTree Code
THYMUS

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.