NCI Definition: A neoplasm that affects the thymus. Representative examples include thymoma and carcinoma. [1]

Thymus neoplasms most frequently harbor alterations in TP53, CDKN2A, KMT2D, NOTCH1, and CDKN2B [2].

Most Commonly Altered Genes in Thymus Neoplasm

TP53 Mutation, TP53 c.217-c.1178 Missense, TP53 Missense, KMT2D Mutation, and NOTCH1 Mutation are the most common alterations in thymus neoplasm [2].

Top Alterations in Thymus Neoplasm

Disease Details

Neoplasm of Thymus, Tumor of Thymus, Thymus Tumor, Thymic Neoplasm, Thymic Tumor, Tumor of the Thymus, Neoplasm of the Thymus
Thymus Disorder
Thymic Epithelial Neoplasm and Malignant Thymus Neoplasm
OncoTree Name
OncoTree Code


1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.