Overview

NCI Definition: Histologic transformation of an indolent non-Hodgkin lymphoma to an aggressive non-Hodgkin lymphoma. [1]

Significant Genes in Transformed Non-Hodgkin Lymphoma

ALK +

BCL2 +

BCL6 +

CCND1 +

CD274 +

IGH +

IRF4 +

MYC +

Disease Details

Parent(s)
Non-Hodgkin Lymphoma
Children
Richter Syndrome

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.