Overview

NCI Definition: An aggressive malignant mixed epithelial and mesenchymal tumor that arises from the uterine corpus. It usually affects elderly postmenopausal women and presents with vaginal bleeding. It is characterized by the presence of a malignant epithelial component that is usually glandular and a sarcomatous component. [1]

Significant Genes in Uterine Corpus Carcinosarcoma

ERBB2 +

POLE +

Disease Details

Synonyms
Carcinosarcoma of the Corpus Uteri, Malignant Mixed Mesodermal Tumor of Uterine Corpus, Uterine Corpus Malignant Mixed Müllerian Tumor, Carcinosarcoma of Uterine Corpus, Uterine Corpus Malignant Mixed Mesodermal Tumor, Uterine Malignant Mixed Mesodermal Neoplasm, Uterine Mixed Mullerian Sarcoma, Carcinosarcoma of Uterus, Uterine Corpus Malignant Mixed Mullerian Tumor, Malignant Mixed Mesodermal Tumor of Uterine Body, Malignant Mixed Mesodermal Neoplasm of the Uterus, Uterine Carcinosarcoma, Uterine Corpus Malignant Mixed Mesodermal Neoplasm, Carcinosarcoma of the Uterine Corpus, Uterine Body Malignant Mixed Mesodermal Tumor, Carcinosarcoma of the Uterine Body, Uterine Body Carcinosarcoma, Malignant Mixed Mesodermal Neoplasm of Uterine Corpus, Uterine Corpus Malignant Mixed Mullerian Neoplasm, Malignant Mixed Mesodermal Neoplasm of the Uterine Corpus, Carcinosarcoma of Uterine Body, Malignant Mixed Mesodermal Neoplasm of the Uterine Body, Malignant Mixed Mesodermal Tumor of Uterus, Malignant Mixed Mesodermal Neoplasm of Uterine Body, Corpus Uteri Malignant Mixed Mesodermal Tumor, Uterine Corpus Malignant Mixed Mesodermal (Mullerian) Tumor, Uterine Corpus Malignant Mixed Mesodermal (Müllerian) Tumor, Mixed Mullerian Sarcoma of Uterus, Carcinosarcoma of Corpus Uteri, Mixed Müllerian Sarcoma of the Uterus, Mixed Mullerian Sarcoma of the Uterus, Uterine Malignant Mixed Mesodermal Tumor, Uterine Corpus Malignant Mixed Müllerian Neoplasm, Malignant Mixed Mesodermal Tumor of the Uterus, Carcinosarcoma of the Uterus, Malignant Mixed Mesodermal Tumor of the Uterine Corpus, Mixed Müllerian Sarcoma of Uterus, Uterine Mixed Müllerian Sarcoma, Malignant Mixed Mesodermal Neoplasm of Uterus, Malignant Mixed Mesodermal Tumor of the Uterine Body, Uterine Body Malignant Mixed Mesodermal Neoplasm
Parent(s)
Uterine Carcinosarcoma
OncoTree Name
Uterine Carcinosarcoma/Uterine Malignant Mixed Mullerian Tumor
OncoTree Code
UCS

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.