NCI Definition: An epithelial neoplasm with neuroendocrine differentiation that arises from the uterine corpus. It includes carcinoid tumor, small cell carcinoma pulmonary type, and large cell neuroendocrine carcinoma. [1]

Uterine corpus neuroendocrine neoplasms most frequently harbor alterations in TP53, PIK3CA, RB1, PTEN, and NOTCH1 [2].

Most Commonly Altered Genes in Uterine Corpus Neuroendocrine Neoplasm

TP53 c.217-c.1178 Missense, TP53 Mutation, TP53 Missense, PIK3CA Mutation, and PTEN Mutation are the most common alterations in uterine corpus neuroendocrine neoplasm [2].

Top Alterations in Uterine Corpus Neuroendocrine Neoplasm

Disease Details

Uterine Corpus Neoplasm
Uterine Corpus Carcinoid Tumor and Endometrial Neuroendocrine Carcinoma


1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.