Overview

Uterine sarcomas most frequently harbor alterations in TP53, RB1, ATRX, PTEN, and CDKN2A [2].

Most Commonly Altered Genes in Uterine Sarcoma

TP53 Mutation, TP53 c.217-c.1178 Missense, TP53 Missense, RB1 Loss, and ATRX Mutation are the most common alterations in uterine sarcoma [2].

Top Alterations in Uterine Sarcoma

Disease Details

Synonyms
Uterus sarcoma (NOS)
Parent(s)
Malignant Uterine Neoplasm
Children
Cervical Sarcoma and Uterine Corpus Sarcoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.