NCI Definition: A neoplasm that affects the uvea. Uveal melanoma is a representative example. [1]

Uveal neoplasms most frequently harbor alterations in GNA11, GNAQ, BAP1, SF3B1, and EIF1AX [2].

Most Commonly Altered Genes in Uveal Neoplasm

GNA11 Mutation, GNA11 Exon 5 Mutation, GNA11 Codon 209 Missense, GNA11 Q209L, and GNAQ Mutation are the most common alterations in uveal neoplasm [2].

Top Alterations in Uveal Neoplasm

Disease Details

Tumor of the Uvea, Tumor of Uvea, Neoplasm of the Uvea, Uvea Tumor, Neoplasm of Uvea, Uveal Tumor, Uvea Neoplasm
Uveal Disorder
Choroid Neoplasm, Ciliary Body Neoplasm, Iris Neoplasm, and Malignant Uveal Neoplasm


1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.