NCI Definition: An aggressive mixed epithelial and mesenchymal neoplasm that arises from the vagina and is characterized by the presence of a malignant epithelial component and a malignant mesenchymal component. 
There is 1 clinical trial for vaginal carcinosarcoma, of which 1 is open and 0 are completed or closed. Of the trial that contains vaginal carcinosarcoma as an inclusion criterion, 1 is phase 2 (1 open).
Cabozantinib, ipilimumab, and nivolumab are the most common interventions in vaginal carcinosarcoma clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.