Vulvar Squamous Intraepithelial Lesion
Associated Genetic Biomarkers
NCI Definition: An intraepithelial lesion of the vulvar squamous epithelium commonly associated with HPV infection. It includes low and high grade squamous intraepithelial lesions. Low grade squamous intraepithelial lesion is considered a non-neoplastic lesion. High grade squamous intraepithelial lesion is neoplastic. 
There is 1 clinical trial for vulvar squamous intraepithelial lesion, of which 1 is open and 0 are completed or closed. Of the trial that contains vulvar squamous intraepithelial lesion as an inclusion criterion, 1 is phase 2 (1 open).
Hpv-16 e7 tcr expressing t-cells is the most common intervention in vulvar squamous intraepithelial lesion clinical trials.
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.