Overview

NCI Definition: Lymphoplasmacytic lymphoma associated with bone marrow involvement and IgM monoclonal gammopathy. [1]

Significant Genes in Waldenstrom Macroglobulinemia

ABL1 +

AFF1 +

BCL2 +

BCL6 +

BCR +

BTK +

CCND1 +

CXCR4 +

DEK +

ELL +

ETV6 +

FGFR3 +

FLT3 +

IGH +

IRAK1 +

JAK2 +

JAK3 +

KMT2A +

MAF +

MECOM +

MLLT1 +

MLLT10 +

MLLT3 +

MLLT4 +

MYC +

MYD88 +

NUP214 +

PLCG2 +

RPN1 +

TP53 +

TYK2 +

Disease Details

Synonyms
Waldenstrom's macroglobulinemia, Waldenstroem's macroglobulinemia, Waldenstroem macroglobulinemia, Waldenström Macroglobulinemia, Lymphoma Waldenstroms, Waldenstrom's Macroglobulinemia
Parent(s)
Lymphoplasmacytic Lymphoma
OncoTree Name
Waldenstrom Macroglobulinemia
OncoTree Code
WM

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.