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Well Differentiated Liposarcoma

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Overview

NCI Definition: A locally aggressive malignant neoplasm composed of mature adipocytes showing cell size variation and nuclear atypia. It is often associated with the presence of hyperchromatic multinucleated stromal cells, and varying numbers of lipoblasts. There are three histologic subtypes, sclerosing, inflammatory, and spindle cell liposarcoma. These tumors do not usually metastasize unless they undergo dedifferentiation. [1]

Clinical Trials

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Disease Details

Synonyms
Well-Differentiated Liposarcoma, Well Differentiated Liposarcoma of Deep Soft Tissue
Parent(s)
Liposarcoma
Children
Spindle Cell Liposarcoma, Inflammatory Liposarcoma, and Sclerosing Liposarcoma
OncoTree Name
Well-Differentiated Liposarcoma
OncoTree Code
WDLS

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.