Diseases /
WHO Grade III Glioma
Back to Diseases List
Associated Genetic Biomarkers
Overview
NCI Definition: A group of malignant gliomas that includes anaplastic astrocytoma, anaplastic oligodendroglioma, anaplastic oligoastrocytoma, and anaplastic ependymoma. [1]
WHO grade III gliomas most frequently harbor alterations in IDH1, TP53, ATRX, CIC, and CDKN2A [2].
IDH1 Mutation, IDH1 Codon 132 Missense, IDH1 R132H, TP53 Mutation, and TP53 Missense are the most common alterations in WHO grade III glioma [2].
Clinical Trials
Significant Genes in WHO Grade III Glioma
Disease Details
References
1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.