Overview

NCI Definition: A group of malignant gliomas that includes anaplastic astrocytoma, anaplastic oligodendroglioma, anaplastic oligoastrocytoma, and anaplastic ependymoma. [1]

Significant Genes in WHO Grade III Glioma

ATRX +

EGFR +

ERBB2 +

IDH1 +

IDH2 +

PDGFA +

PDGFB +

PDGFRA +

PDGFRB +

TP53 +

Disease Details

Synonyms
Anaplastic Glioma
Parent(s)
Malignant Glioma
Children
Anaplastic Pleomorphic Xanthoastrocytoma, Anaplastic Ependymoma, Anaplastic Oligoastrocytoma, Anaplastic Astrocytoma, and Anaplastic Oligodendroglioma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.