Overview

NCI Definition: A group of malignant gliomas that includes anaplastic astrocytoma, anaplastic oligodendroglioma, anaplastic oligoastrocytoma, and anaplastic ependymoma. [1]

Significant Genes in WHO Grade III Glioma

ATRX +

EGFR +

ERBB2 +

IDH1 +

IDH2 +

PDGFA +

PDGFB +

PDGFRA +

PDGFRB +

TP53 +

Disease Details

Synonyms
Anaplastic Glioma
Parent(s)
Malignant Glioma
Children
Anaplastic Oligodendroglioma, Anaplastic Astrocytoma, Anaplastic Ependymoma, and Anaplastic Oligoastrocytoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.