Overview

NCI Definition [1]:
A synthetic p-aminophenol derivative and diphenhydramine combination with anti-inflammatory, analgesic, and anti-allergic properties. Acetaminophen Diphenhydramine is used to treat symptoms of allergies and hay fever. The active principal metabolite of phenacetin, acetaminophen appears to inhibit prostaglandin biosynthesis in the central nervous system and less in peripheral tissues. Diphenhydramine blocks histamine effects, preventing sneezing and itchy, watery eyes, as well as nasal and other allergy and hay fever symptoms. (NCI04)

Acetaminophen/diphenhydramine has been investigated in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial investigating acetaminophen/diphenhydramine, 1 is phase 2 (1 open).

Non-small cell lung carcinoma is the most common disease being investigated in acetaminophen/diphenhydramine clinical trials [2].

Drug Details

Synonyms [2]:
acetaminophen/diphenhydramine, acetaminophen / diphenhydramine, paracetamol+diphenhydramine, acetaminophen / diphenhydramine, diphenhydramine + paracetamol, acetaminophen+diphenhydramine, acetaminophen+diphenhydramine (product)
NCIT ID [1]:
C28808
SNOMED ID [1]:
C-5146B

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/. [2018-07-30] [2018-08-02].

2. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.