Drugs /
atovaquone
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Overview
NCI Definition [1]:
A synthetic hydroxynaphthoquinone with antiprotozoal activity. Atovoquone blocks the mitochondrial electron transport at complex III of the respiratory chain of protozoa, thereby inhibiting pyrimidine synthesis, preventing DNA synthesis and leading to protozoal death.
Clinical Trials
Atovaquone has been investigated in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial investigating atovaquone, 1 is early phase 1 (1 open).
Drug Details
Synonyms [2]:
2-(4-(4'-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone, 2-(trans-4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone, atovaquone, atovaquone (substance), hydroxynaphthoquinone, 566c80, mepron, hydroxynaphthoquinone 566c80, atovaquone, 2-(trans-4-(p-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone, bw-566c, 3-(4-(4-chlorophenyl)cyclohexyl)-4-hydroxy-naphthalene-1,2-dione, wellvone, atovaquone (product), 566c80, bw-a566c, 566c80 hydroxynaphthoquinone, atovaquone [chemical/ingredient]
NCIT ID [1]:
C28838
SNOMED ID [1]:
F-61AFD
References
1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/. [2018-07-30] [2018-08-02].
2. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.
