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dexamethasone

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Overview

Generic Name(s):
dexamethasone
Trade Name(s):
Dexafluorene, Fortecortin, Aeroseb-Dex, Ambene, Deltafluorene, Dekacort, Visumetazone, Decasone R.P., Maxidex, Dexacortin, Adexone, Dexa-Sine, Alba-Dex, Dexapos, Dezone, Deenar, Hexadrol, Dectancyl, Alin, Dexameth, Sk-Dexamethasone, Decaderm, Deronil, Mymethasone, Orgadrone, Dexamecortin, Decameth, Anemul Mono, Auxiloson, Dexone, Decadrol, Dexa-Scheroson, Dexacortal, Dexafarma, Desameton, Dexace, Decacort, Dex-4, Loverine, Alin Depot, Dexinoral, Millicorten, Dexa-Mamallet, Dinormon, Predni-F, Alin Oftalmico, Corson, Antimicotico, Aknichthol Dexa, Dexa-Rhinosan, Fluorodelta, Auricularum, Decalix, Spersadex, Cortidexason, Azona, Decadron, Baycuten N, Dexamonozon, Aacidexam, Amplidermis, Ocasa, Decaspray, Gammacorten, Baycuten, Dexalocal, Lokalison-F, Cortisumman, and Aquapred
NCI Definition [1]:
A synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones. (NCI04)

Clinical Trials

View Clinical Trials for dexamethasone

Dexamethasone has been investigated in 255 clinical trials, of which 228 are open and 27 are closed. Of the trials investigating dexamethasone, 1 is early phase 1 (1 open), 49 are phase 1 (42 open), 46 are phase 1/phase 2 (40 open), 107 are phase 2 (97 open), 6 are phase 2/phase 3 (6 open), 40 are phase 3 (36 open), 3 are phase 4 (3 open), and 3 are no phase specified (3 open).

BCR-ABL1 Fusion, t(9;22)(q34;q11), and del(17)(p10) are the most frequent biomarker inclusion criteria for dexamethasone clinical trials.

Multiple myeloma, acute lymphoblastic leukemia, and B-cell acute lymphoblastic leukemia are the most common diseases being investigated in dexamethasone clinical trials [2].

Top Biomarker Inclusion Criteria for Open Clinical Trials Investigating Dexamethasone
Top Biomarker Inclusion Criteria for Closed Clinical Trials Investigating Dexamethasone
This graph displays the 20 most frequently occurring biomarkers curated on clinical trials investigating dexamethasone and the cancer types associated with these biomarkers. These numbers are derived from a set of 5,956 clinical trials for which biomarker status defines treatment.

Drug Details

Synonyms [2]:
Dexalocal, Dexafluorene, Alba-Dex, Decaderm, Decadrol, Decadron, Decasone R.p., Decaspray, Deenar, Deronil, Dex-4, Dexace, Dexameth, Dezone, Gammacorten, Hexadrol, Aeroseb-Dex, Maxidex, Sk-Dexamethasone, Dexinoral, Dexone, Dinormon, Fluorodelta, Fortecortin, Lokalison-F, Loverine, Millicorten, Mymethasone, hexadecadrol, 1-dehydro-16alpha-methyl-9alpha-fluorohydrocortisone, dexamethasone [chemical/ingredient], 34521, Auricularum, Aquapred, Antimicotico, Decalix, Decacort, Cortisumman, Cortidexason, Corson, Baycuten N, Baycuten, Azona, Auxiloson, Alin, Visumetazone, Spersadex, Predni-F, Orgadrone, Ocasa, Dexa-sine, Dexa-Scheroson, Dexa-Rhinosan, Dexapos, Dexamonozon, 16alpha-methyl-9alpha-fluoro-delta1-hydrocortisone, 50-02-2, pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11beta,16alpha)-, dxm, 16alpha-methyl-9alpha-fluoro-1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione, decasone r.p., 9alpha-fluoro-16alpha- methylprednisolone, 9alpha-fluoro-16alpha-methylprednisolone, 9alpha-fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, (11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-fluoro-16α-methylprednisolone, foy brand of dexamethasone, 16α-methyl-9α-fluoro-1-dehydrocortisol, dexamethasone preparation (product), 16alpha-methyl-9alpha-fluoro-delta1-hydrocortisone, dexamethasone preparation, (11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, methylfluorprednisolone, dexamethasone, dexametasona, 16alpha-methyl-9alpha-fluoro-1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione, 16alpha-methyl-9alpha-fluoroprednisolone, Dexamecortin, Dexa-Mamallet, Dexafarma, Dexacortin, Dexacortal, Desameton, dm, 1-dehydro-16alpha-methyl-9alpha-fluorohydrocortisone, fluoro-9alpha methyl-16alpha prednisolone, desamethasone, 1-dehydro-16α-methyl-9α-fluorohydrocortisone, dexamethasone (substance), 9alpha-fluoro-16alpha-methylprednisolone, 16alpha-methyl-9alpha-fluoroprednisolone, dexamethasone, 9alpha-fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, spersadox, 16alpha-methyl-9alpha-fluoro-1-dehydrocortisol, disaimisong, dexamethasonum, Aacidexam, Adexone, Aknichthol Dexa, Deltafluorene, Dekacort, Dectancyl, Decameth, Anemul mono, Amplidermis, Ambene, Alin Oftalmico, Alin Depot
Drug Categories [2]:
Corticosteroids
NCIT ID [1]:
C422
SNOMED ID [1]:
C-A0250

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/. [2018-07-30] [2018-08-02].

2. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.