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ethinyl estradiol

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Overview

NCI Definition [1]:
A semisynthetic estrogen. Ethinyl estradiol binds to the estrogen receptor complex and enters the nucleus, activating DNA transcription of genes involved in estrogenic cellular responses. This agent also inhibits 5-alpha reductase in epididymal tissue, which lowers testosterone levels and may delay progression of prostatic cancer. In addition to its antineoplastic effects, ethinyl estradiol protects against osteoporosis. In animal models, short-term therapy with this agent has been shown to provide long-term protection against breast cancer, mimicking the antitumor effects of pregnancy. (NCI04)

Clinical Trials

View Clinical Trials for ethinyl estradiol

Ethinyl estradiol has been investigated in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial investigating ethinyl estradiol, 1 is phase 1 (1 open).

Diffuse large B-cell lymphoma, follicular lymphoma, and lymphoplasmacytic lymphoma are the most common diseases being investigated in ethinyl estradiol clinical trials [2].

Drug Details

Synonyms [2]:
17alpha-ethinyl estradiol, ethinyl estradiol, ethynylestradiol, ethinyloestradiol, ethinoral, 17α-ethynylestradiol, 17 alpha-ethynyloestradiol, eticylol, 57-63-6, diogyn-e, ethynyl estradiol, ethynyloestradiol, ethinyloestradiol product, organon brand of ethinyl estradiol, orestralyn, ethinyl estradiol, 17-ethinylestradiol, 10973, (17alpha)-19-norpregna-1,3,5(10)-trien-20-yne-3,17-diol, 17-ethinyl-3,17-oestradiol, ethinylestradiol, schering-plough brand of ethinyl estradiol, lynoral, ethinyl estradiol preparation (product), ethinyl oestradiol preparation, 17 alpha-ethinylestradiol, ee, (17alpha)-19-norpregna-1,3,5(10)-trien-20-yne-3,17-diol, inestra, ethinyl-oestranol, ethinylestriol, estradiol, ethinyl, ethinylestradiol, ethinylestradiol product, feminone, ethinyl estradiol [chemical/ingredient], estradiol, ethynyl, ethinyl estradiol, ethynylestradiol, etinilestradiol, 7259, ethinyl estradiol (substance), ethinyl estradiol preparation, 19-norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha)-, ethynyl estradiol, 17 alpha-ethynylestradiol, diogyn e, estinyl, 17-ethinyl-3,17-estradiol, ethinylestradiolum
NCIT ID [1]:
C486
SNOMED ID [1]:
C-A0710

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/. [2018-07-30] [2018-08-02].

2. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.