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interferon gamma

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Overview

NCI Definition [1]:
Interferon gamma (166 aa, ~19 kDa) is encoded by the human IFNG gene. This protein is involved in antiviral activity, macrophage activation, antiproliferative activity and immunopotentiation.

Clinical Trials

View Clinical Trials for interferon gamma

Interferon gamma has been investigated in 4 clinical trials, of which 3 are open and 1 is closed. Of the trials investigating interferon gamma, 1 is early phase 1 (1 open), 2 are phase 1 (1 open), and 1 is phase 1/phase 2 (1 open).

ERBB2 Amplification, HER2 Overexpression, and HER2 Positive are the most frequent biomarker inclusion criteria for interferon gamma clinical trials.

Acute myeloid leukemia, breast carcinoma, and malignant solid tumor are the most common diseases being investigated in interferon gamma clinical trials [2].

Top Biomarker Inclusion Criteria for Open Clinical Trials Investigating Interferon Gamma
Top Biomarker Inclusion Criteria for Closed Clinical Trials Investigating Interferon Gamma
This graph displays the 20 most frequently occurring biomarkers curated on clinical trials investigating interferon gamma and the cancer types associated with these biomarkers. These numbers are derived from a set of 5,956 clinical trials for which biomarker status defines treatment.

Drug Details

Synonyms [2]:
gamma interferon (substance), immune interferon, ifn-g, gamma interferon, interferon gamma, interferon gamma (substance), interferon-gamma, interferon, immune, type ii interferon, lfn-gamma, interferon, type ii, gamma-interferon, ifng, immune interferon, interferon type ii, interferon, gamma, gamma-interferon, interferon gamma (human lymphocyte protein moiety reduced), type ii interferon, interferon-gamma [chemical/ingredient], gamma interferon, ifng, gamma interferon, interferon gamma, interferon, gamma, interferon gamma (product), interferon.gamma
Drug Target(s) [2]:
IFNGR1, IFNGR2
NCIT ID [1]:
C20496
SNOMED ID [1]:
F-CB530

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/. [2018-07-30] [2018-08-02].

2. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.