Drugs /

methionine-restricted diet

Back to Drugs List

Overview

NCI Definition [1]:
A diet which is limited in the amino acid methionine. Methionine depletion inhibits cell cycle progression and induces apoptosis in many transformed cells, but not normal cells. Dietary methionine restriction inhibits tumor growth in diverse cancer models and is in trial as part of clinical cancer treatments.

Clinical Trials

View Clinical Trials for methionine-restricted diet

Methionine-restricted diet has been investigated in 1 clinical trial, of which 0 are open and 1 is closed. Of the trial investigating methionine-restricted diet, 1 is phase 2 (0 open).

ER Negative, ER No Expression, and HER2 Deficient Expression are the most frequent biomarker inclusion criteria for methionine-restricted diet clinical trials.

Breast carcinoma is the most common disease being investigated in methionine-restricted diet clinical trials [2].

Top Biomarker Inclusion Criteria for Closed Clinical Trials Investigating Methionine-Restricted Diet
This graph displays the 20 most frequently occurring biomarkers curated on clinical trials investigating methionine-restricted diet and the cancer types associated with these biomarkers. These numbers are derived from a set of 5,956 clinical trials for which biomarker status defines treatment.

Drug Details

NCIT ID [1]:
C154555

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/. [2018-07-30] [2018-08-02].

2. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.