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methoxsalen

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Overview

NCI Definition [1]:
A naturally occurring substance isolated from the seeds of the plant Ammi majus with photoactivating properties. As a member of the family of compounds known as psoralens or furocoumarins, methoxsalen's exact mechanism of action is unknown; upon photoactivation, methoxsalen has been observed to bind covalently to and crosslink DNA. (NCI04)

Clinical Trials

View Clinical Trials for methoxsalen

Methoxsalen has been investigated in 3 clinical trials, of which 3 are open and 0 are closed. Of the trials investigating methoxsalen, 1 is phase 2 (1 open), 1 is phase 2/phase 3 (1 open), and 1 is phase 3 (1 open).

ER Expression, ER Positive, and HER2 Deficient Expression are the most frequent biomarker inclusion criteria for methoxsalen clinical trials.

Pancreatic adenocarcinoma and breast carcinoma are the most common diseases being investigated in methoxsalen clinical trials [2].

Top Biomarker Inclusion Criteria for Open Clinical Trials Investigating Methoxsalen
This graph displays the 20 most frequently occurring biomarkers curated on clinical trials investigating methoxsalen and the cancer types associated with these biomarkers. These numbers are derived from a set of 5,956 clinical trials for which biomarker status defines treatment.

Drug Details

Synonyms [2]:
canderm brand of methoxsalen, 8mop, methoxsalen delta brand, zanthotoxin, methoxsalen, 45923, icn brand 1 of methoxsalen, ammoidin, puvasoralen, ultramop, 298-81-7, méthoxsalène, db brand of methoxsalen, 8-methoxy-4',5':6,7-furocoumarin, methoxsalen canderm brand, methoxsalen chinoin brand, dermox, 7h-furo(3,2-g)(1)benzopyran-7-one, 9-methoxy-, dermatech brand of methoxsalen, methoxsalen mex-america brand, boehringer ingelheim brand of methoxsalen, 8-methoxypsoralen, sanofi synthelabo brand of methoxsalen, sanofi-synthelabo brand of methoxsalen, methoxsalen dermatech brand, 8 mop, methoxsalen, ultra mop, xanthotoxin, meladinina, methoxsalen (product), metoxaleno, meladinine, icn brand 3 of methoxsalen, xanthotoxine, 9-methoxy-7h-furo[3,2-g][1]benzopyran-7-one, 8-methoxypsoralen, delta brand of methoxsalen, icn brand 2 of methoxsalen, 8-methoxy-2',3',6,7-furocoumarin, methoxypsoralen 08, chinoin brand of methoxsalen, mex-america brand of methoxsalen, 6-hydroxy-7-methoxy-5-benzofuranacrylic acid delta-lactone, galderma brand of methoxsalen, methoxypsoralen, methoxsalen sanofi-synthelabo brand, 8 methoxypsoralen, 8-methoxyfuranocoumarin, deltasoralen, mex america brand of methoxsalen, méladinine, 8-methoxy-[furano-3'.2':6.7-coumarin], 8-mp, methoxsalen [chemical/ingredient], oxsoralen ultra, uvadex, 8-mop, geroxalen, methoxsalen (substance), oxsoralen-ultra, mopsoralen, geralen, xanthotoxin, oxsoralen, o-methylxanthotoxol
NCIT ID [1]:
C643
SNOMED ID [1]:
C-92820

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/. [2018-07-30] [2018-08-02].

2. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.