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muscadine grape skin extract

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Overview

NCI Definition [1]:
A nutritional supplement containing an extract of the skin of Muscadine grape (Vitis rotundifolia), with anti-inflammatory, antioxidant and potential chemopreventive activities. The skin extract of the muscadine grape contains numerous phytochemicals including hydrolyzable tannins and flavonoids, such as anthocyanin 3,5-diglucosides, quercetin, myricetin, and kaempferol glycosides. Upon administration, muscadine grape skin extract (MSKE) appears to inhibit PI3K/Akt and MAPK signaling, eventually leading to apoptosis and a reduction in tumor cell proliferation.

Clinical Trials

View Clinical Trials for muscadine grape skin extract

Muscadine grape skin extract has been investigated in 2 clinical trials, of which 2 are open and 0 are closed. Of the trials investigating muscadine grape skin extract, 1 is phase 2 (1 open) and 1 is phase 3 (1 open).

Prostate adenocarcinoma is the most common disease being investigated in muscadine grape skin extract clinical trials [2].

Drug Details

Synonyms [2]:
muscadine plus, vinetra, mske
NCIT ID [1]:
C96231

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/. [2018-07-30] [2018-08-02].

2. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.