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recombinant interferon alfa-2b

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Overview

NCI Definition [1]:
A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects.

Clinical Trials

View Clinical Trials for recombinant interferon alfa-2b

Recombinant interferon alfa-2b has been investigated in 8 clinical trials, of which 7 are open and 1 is closed. Of the trials investigating recombinant interferon alfa-2b, 1 is early phase 1 (1 open), 2 are phase 1 (2 open), 1 is phase 1/phase 2 (0 open), and 4 are phase 2 (4 open).

ER Negative, ER No Expression, and HER2 Deficient Expression are the most frequent biomarker inclusion criteria for recombinant interferon alfa-2b clinical trials.

Breast carcinoma, colorectal carcinoma, and melanoma are the most common diseases being investigated in recombinant interferon alfa-2b clinical trials [2].

Top Biomarker Inclusion Criteria for Open Clinical Trials Investigating Recombinant Interferon Alfa-2b
Top Biomarker Inclusion Criteria for Closed Clinical Trials Investigating Recombinant Interferon Alfa-2b
This graph displays the 20 most frequently occurring biomarkers curated on clinical trials investigating recombinant interferon alfa-2b and the cancer types associated with these biomarkers. These numbers are derived from a set of 5,956 clinical trials for which biomarker status defines treatment.

Drug Details

Synonyms [2]:
sch 30500, interferon alpha-2b, urifron, interferon alpha-2b, recombinant, interferon alfa-2b, sch-30500, ifn alpha-2b, intron a (interferon α2b), interferon alfa-2b [chemical/ingredient], intron a, interferon alfa 2-b, heberon alfa, interferon alpha-2b preparation (product), recombinant interferon alpha-2b, interferon α-2b, ifnalpha-2b, recombinant, interferon alfa-2b, intron (interferon α2b), interferon alfa-2b,recombinant, alfatronol, intron a, interferon alpha-2b, rifn-alpha-2b, interferon alfa-2b, interferon alfa-2b, interferon alfa-2b, recombinant, recombinant interferon alfa-2b, interferon alpha-2b (substance), interferon alpha-2b, interferon alfa-2b, viraferon, glucoferon, interferon alpha-2b preparation, interferon alfa-2b, intron a (interferon), interferon alfa 2b
NCIT ID [1]:
C1953
SNOMED ID [1]:
C-55B79

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/. [2018-07-30] [2018-08-02].

2. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.