Drugs /

triptorelin

Back to Drugs List

Overview

Generic Name(s):
triptorelin
Trade Name(s):
Trelstar
NCI Definition [1]:
A synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. (NCI04)

Clinical Trials

View Clinical Trials for triptorelin

Triptorelin has been investigated in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial investigating triptorelin, 1 is phase 2 (1 open).

AR Expression and AR Positive are the most frequent biomarker inclusion criteria for triptorelin clinical trials.

Adenocarcinoma of unknown primary and salivary duct carcinoma are the most common diseases being investigated in triptorelin clinical trials [2].

Top Biomarker Inclusion Criteria for Open Clinical Trials Investigating Triptorelin
This graph displays the 20 most frequently occurring biomarkers curated on clinical trials investigating triptorelin and the cancer types associated with these biomarkers. These numbers are derived from a set of 5,956 clinical trials for which biomarker status defines treatment.

Drug Details

Synonyms [2]:
cl-118,532, ay 25650, (d-trp6)-gnrh\t, 6-d-tryptophan-luteinizing hormone-releasing factor (pig), pglu-his-trp-ser-tyr-d-trp-leu-arg-pro-gly-nh2\t, (6-d-tryptophan)luteinizing hormone-releasing hormone\t, decapeptyl depot, triptorelin [chemical/ingredient], decapeptyl trimestral, trip, triptorelin (product), decapeptyl, trimestral, decapeptyl, ay-25650, 6-d-tryptophan-lh-rh, lhrh, tryptophyl(6)-, ay25650, triptorelin (substance), cl 118532, triptorelinum, lhrh, trp(6)-, detryptoreline, decapeptyl lp, trp lhrh d 06, cl118532, d-trp-6-lhrh, triptoreline, d-trp-6-lh-rh, gnrh, trp(6)-, triptorelina, 57773-63-4, cl-118532, triptorelin, 6-d-tryptophanluteinizing hormone-releasing factor, triptorelin, luteinizing hormone-releasing factor (pig), 6-d-tryptophan, Trelstar
NCIT ID [1]:
C1267
SNOMED ID [1]:
F-61A0D

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/. [2018-07-30] [2018-08-02].

2. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.