Overview

NCI Definition [1]:
A recombinant vaccinia virus that encodes granulocyte-macrophage colony stimulating factor (GM-CSF). By activating T-cells and macrophages, vaccination with recombinant vaccinia GM-CSF may enhance the host immune system response to poorly immunogenic tumors, resulting in decreased tumor growth. (NCI04)

Vaccinia-gm-csf vaccine has been investigated in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial investigating vaccinia-gm-csf vaccine, 1 is phase 1 (1 open).

Melanoma is the most common disease being investigated in vaccinia-gm-csf vaccine clinical trials [2].

Drug Details

Synonyms [2]:
rv-gm-csf, rv gm-csf, recombinant vaccinia-gm-csf
NCIT ID [1]:
C2674

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/. [2018-07-30] [2018-08-02].

2. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.