Overview

Location [1]
Xp11.22
Protein [2]
A-kinase anchor protein 4
Synonyms [1]
hAKAP82, PRKA4, AKAP82, p82, "AKAP 82", CT99, AKAP-4, FSC1, HI

AKAP4 is altered in 0.01% of all cancers with papillary renal cell carcinoma having the greatest prevalence of alterations [3].

AKAP4 GENIE Cases - Top Diseases

Significance of AKAP4 in Diseases

Chronic Lymphocytic Leukemia +

Hodgkin Lymphoma +

Malignant Solid Tumor +

Multiple Myeloma +

Non-Hodgkin Lymphoma +

Acute Lymphoblastic Leukemia +

Acute Myeloid Leukemia +

Chronic Myeloid Leukemia +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.